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Medical Topic

Ozone Bagging Therapy: Application in Chronic Wounds, Diabetic Foot, and Local Infections

Short answerOzone bagging is the controlled exposure of a wound or problematic extremity to a medical oxygen-ozone mixture by enclosing it within an ozone-resistant closed system. It is investigated as an adjunctive local method to standard wound care.
In this guide

How is it performed? · Respiratory safety · Targets on the wound surface · Human data · If the wound does not close · Relationship with systemic ozone

How is it performed?

The wound is clinically evaluated, necessary standard care is provided, the extremity is placed into a closed, ozone-resistant system, and a controlled local ozone atmosphere is maintained. At the end of the procedure, residual ozone must be passed through a safe destruction system.

Respiratory safety

Inhaling ozone gas is not a treatment; it is a potent respiratory irritant. A closed system and the safe evacuation of residual ozone are fundamental safety requirements.

Targets on the wound surface

Local microbial load, biofilm environment, inflammatory/redox response, and granulation processes are being investigated.

Human data

There is a clinical study reporting that bagging in diabetic foot ulcers can reduce bacterial colonies. In the same study, the difference in wound healing scores remained more limited; this finding suggests that further detailed investigation into the contribution of bagging within combined wound care according to patient selection and application protocol is warranted.

If the wound does not close

Circulation, pressure, glycemic control, osteomyelitis, necrotic tissue, and nutrition should be reevaluated.

Relationship with systemic ozone

Local and systemic ozone have different targets; although they may be considered together in selected patients, they are not equivalent to each other.

Our Approach at Our Bodrum Clinic

During an evaluation with Dr. Kerem Çağlayan in Bodrum, your complaints, medical history, and current treatments are considered together. For those seeking information about ozone bagging in Muğla and Milas, this guide explains the procedure and its areas of use.

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Related ozone applications

References

  1. Ozone therapy on bacterial colonies and diabetic foot ulcer healing. Home Healthc Now. 2020. View source
  2. Izadi M, et al. 2024.
  3. Cacciatore S, et al. 2026.
  4. Madrid Declaration on Ozone Therapy – topical gasification/bagging.

Medical editorial information

This content has been medically reviewed and approved by Dr. Kerem Çağlayan. It is intended for general education and does not replace an individual diagnosis or treatment plan.