How is it performed? · Respiratory safety · Targets on the wound surface · Human data · If the wound does not close · Relationship with systemic ozone
How is it performed?
The wound is clinically evaluated, necessary standard care is provided, the extremity is placed into a closed, ozone-resistant system, and a controlled local ozone atmosphere is maintained. At the end of the procedure, residual ozone must be passed through a safe destruction system.
Respiratory safety
Inhaling ozone gas is not a treatment; it is a potent respiratory irritant. A closed system and the safe evacuation of residual ozone are fundamental safety requirements.
Targets on the wound surface
Local microbial load, biofilm environment, inflammatory/redox response, and granulation processes are being investigated.
Human data
There is a clinical study reporting that bagging in diabetic foot ulcers can reduce bacterial colonies. In the same study, the difference in wound healing scores remained more limited; this finding suggests that further detailed investigation into the contribution of bagging within combined wound care according to patient selection and application protocol is warranted.
If the wound does not close
Circulation, pressure, glycemic control, osteomyelitis, necrotic tissue, and nutrition should be reevaluated.
Relationship with systemic ozone
Local and systemic ozone have different targets; although they may be considered together in selected patients, they are not equivalent to each other.
Our Approach at Our Bodrum Clinic
During an evaluation with Dr. Kerem Çağlayan in Bodrum, your complaints, medical history, and current treatments are considered together. For those seeking information about ozone bagging in Muğla and Milas, this guide explains the procedure and its areas of use.
Related ozone applications
References
- Ozone therapy on bacterial colonies and diabetic foot ulcer healing. Home Healthc Now. 2020. View source
- Izadi M, et al. 2024.
- Cacciatore S, et al. 2026.
- Madrid Declaration on Ozone Therapy – topical gasification/bagging.


