Key points
- Appropriate patient selection and correct parameters are more important than the device brand.
- Each technology affects a different tissue depth and biological target; it may not be necessary to approach the same problem with a single modality.
- Skin quality, laxity, pigment, vascular appearance, wrinkles, acne scars, and contour goals are evaluated individually.
- Minimally invasive or non-invasive methods have a different scope and recovery process than surgical procedures.
- The best plan is not the one with the most procedures performed, but the one where the most appropriate combination is selected according to the individual’s needs.
Which technologies fall into this group?
Laser systems, intense pulsed light, radiofrequency, microneedling radiofrequency, fractional energy systems, microfocused ultrasound, and photobiomodulation can be evaluated within this broad category. In addition, injection procedures such as PN/PDRN are not in the same group as energy-based methods; however, they can be part of a combined plan for skin quality goals.
For what purposes can they be evaluated?
- Fine wrinkles and improvement of skin texture
- Mild–moderate tissue laxity and support of facial contour
- Acne scars and pore appearance
- Selected pigmentary and vascular concerns
- Double chin, jawline, and certain localized contour goals
- Skin quality, hydration, elasticity, and goals of a more vibrant appearance
Undiagnosed skin lesions or newly developing pigment changes should be evaluated dermatologically prior to aesthetic procedures.
How is the method selected?
For example, if laxity and contour goals in the lower face are prominent, subdermal laser/Endolifting may come to the fore. For acne scars, pores, and superficial tissue renewal goals, RF microneedling may be more suitable. For wrinkles, skin quality, or healing support, Red Light/photobiomodulation may assume a different role. PN/PDRN or skin booster procedures, on the other hand, can be evaluated for hydration, tissue quality, and regenerative goals. For the same individual, one of these options or an appropriate combination can be chosen.
Research and clinical approach
There is a broad literature of human studies for energy-based aesthetic technologies. Research reports differing results depending on the device used, wavelength, energy, target tissue, skin type, and follow-up duration. While some methods have a broader database for specific indications, studies for newer technologies are still evolving. Therefore, rather than generalizing outcomes to a brand or a single device name, results are evaluated specifically according to the applied technology and the targeted problem.
Published studies on Endolifting and 1470 nm subdermal laser applications report positive aesthetic outcomes; larger comparative studies will better define which patient groups benefit the most. For RF microneedling, on the other hand, there is a broader clinical literature in the fields of skin resurfacing, acne scars, and tissue quality.
Our approach at our Bodrum clinic
During the initial consultation, before the question of “which device?”, the question of “which goal, which anatomical plane, and which natural look?” is answered. Skin type, facial anatomy, tissue thickness, previous procedures, tendency for scarring and pigmentation, medications used, and the downtime that can be allocated for recovery are evaluated.
The goal is not to alter the individual’s facial expression, but, when appropriate, to support a more rested, balanced, and natural appearance. Rather than applying a single method to everyone, Endolifting, RF microneedling, Red Light, PN/PDRN, skincare protocols, or surgical options when necessary are compared with one another.
Safety and potential side effects
Temporary redness, edema, tenderness, bruising, or crusting may be observed depending on the method used. In energy-based procedures, more significant complications such as burns, pigmentary changes, infection, scarring, contour irregularities, loss of adipose tissue, or nerve involvement are possible, although rare. The risk is closely related to energy, depth of delivery, anatomical region, skin type, and practitioner experience.
In 2025, the FDA highlighted certain serious complications reported with radiofrequency microneedling procedures. For this reason, particularly in RF microneedling, device settings, depth of delivery, and patient selection must be meticulously planned.
Frequently asked questions
Which skin rejuvenation method is better?
A single method is not best for everyone. Goals such as laxity, wrinkles, pigment, acne scars, pores, or skin quality may require different technologies.
Can results be achieved in a single session?
In some procedures, initial changes may be seen early. The magnitude and maturation of the result, as well as how many sessions will be required, vary depending on the method and the individual’s tissue characteristics.
Can the methods be applied together?
Yes, in suitable candidates, methods targeting different objectives can be planned in stages or in combination. The timing and intensity of the combination are determined according to the skin’s healing capacity.
Application and comparison guides
- Skin rejuvenation and wrinkle treatments
- Endolifting
- Endolifting or RF microneedling?
- Red Light therapy and photobiomodulation
- Salmon DNA / PN-PDRN
- Salmon DNA or Skinbooster?
- Skin aging and wrinkles
References
- U.S. FDA. Potential Risks with Certain Uses of Radiofrequency Microneedling. 2025. Safety communication
- Jia X, ve ark. Energy-Based Skin Rejuvenation: A Review of Mechanisms and Thermal Effects. 2024. PMC
- Sanyal RD, ve ark. Energy-Based Devices for Facial Skin Conditions in Skin Types III–VI. 2024. PubMed
- Nilforoushzadeh MA, ve ark. The Endo-lift Laser (Intralesional 1470 nm Diode Laser): A Systematic Review. 2024. PubMed
Written and medically reviewed by: Dr. Kerem Çağlayan
Last medical review: September 10, 2026
Disclaimer: This content is for general health information purposes only; it is not a personal diagnosis or treatment recommendation. Results may vary from person to person, and a physician evaluation is required prior to the procedure.