MRI and symptom correlation
Visualizing a disc protrusion/herniation on MRI does not mean it is the definitive source of pain. Disc, nerve root, facet, sacroiliac joint, muscle, and hip origins must be differentiated.
Paravertebral ozone
It targets the paraspinal muscles/soft tissues around the spine. In a small double-blind placebo-controlled study, positive results in pain/function were reported when added to standard treatment.
Intradiscal ozone
It is an interventional procedure performed directly into the disc under imaging guidance; sterile intervention, proper disc selection, and radiological targeting are required.
2025 meta-analysis
In 8 RCTs and 1,744 patients, intradiscal ozone was found to have favorable short-term results in VAS pain and ODI functional outcomes.
Surgical indications
If there is progressive muscle weakness, severe motor deficit, cauda equina signs, or severe functional loss despite appropriate conservative treatment, surgical evaluation should not be delayed.
New combination data
In a 2026 randomized study, the addition of periradicular ozone to endoscopic discectomy was associated with additional improvement in some parameters in the early period; this does not mean it is an alternative to surgery.
Our Approach in Our Bodrum Clinic
For those seeking information on this topic in Muğla and Milas, this guide explains application methods along with clinical evaluation. In the individualized physician evaluation in Bodrum, health history, current treatments, and expectations are addressed together.
Related ozone guides
Ozone therapy: methods and clinical approach · All ozone guides
