Myofascial target · Principle of administration · Difference from acupuncture · Human data · Difference from paravertebral · Red flags
Myofascial target
Some pains may originate from local trigger points rather than a broad anatomical area. Muscle tension, tenderness, and referred pain may coexist; accurately determining the treatment target is important for the success of local administration.
Principle of administration
Pain mapping, muscle bands, and anatomical targets are determined. Imaging is used when necessary. Local ozone is planned as an application that complements the clinical diagnosis and can be used on selected anatomical targets.
Difference from acupuncture
Some Ashi or acupuncture points can be used as anatomical targets; the ozone microdose approach, unlike classical acupuncture, involves using a controlled medical oxygen–ozone mixture as a local biological stimulus.
Human data
In a 2007 randomized study of 120 patients with low back pain, the administration of ozone to acupuncture points was found to be associated with short-term positive outcomes. This direct human data supports the potential of the method; up-to-date, independent, and more detailed studies will help clarify in which patient groups the effect is more pronounced.
Difference from paravertebral administration
Paravertebral administration may cover broader paraspinal targets; the microdose approach is focused on local tender points. The two methods can be evaluated separately according to the individual’s pain pattern or, in appropriate cases, as different components of the same treatment plan.
Red flags
If there is night pain, loss of strength, fever, trauma, history of cancer, or neurological deficit, the underlying cause is investigated first. These findings require an appropriate diagnostic evaluation.
Our Approach in Our Bodrum Clinic
In ozone microdose administration, we first determine the anatomical source of pain and the trigger point pattern. In appropriate patients, we personalize local administration along with exercise, manual approaches, and other pain treatments.
Related ozone applications
References
- Zhang Y, Chen F, Wu S. O3 acupoint injection for low back pain. Zhongguo Zhen Jiu. 2007. View source
- Madrid Declaration on Ozone Therapy.


