Bladder pain syndrome · How is it administered? · Human study · Limitation of evidence · Guideline status · Distinction from bacterial cystitis
Bladder pain syndrome
Chronic bladder-related pain/pressure, frequent urination, and urgency may be seen. Standard cultures may not always show infection; recurrent antibiotics are not appropriate for every patient.
How is it administered?
After evaluating for active infection, hematuria, stones, tumors, and other urological causes, local administration is performed via a sterile catheter. The target is the bladder mucosa and the local inflammatory environment.
Human study
In a prospective preliminary study of 16 patients who did not respond to conventional treatments, a significant reduction in symptom scores and a favorable response lasting up to 6 months were reported.
Limitation of evidence
The study is small, uncontrolled, and preliminary. A definitive conclusion regarding efficacy cannot be drawn without larger randomized trials.
Guideline status
In the AUA interstitial cystitis/bladder pain syndrome guideline, ozone is not a standard recommended treatment.
Distinction from bacterial cystitis
Recurrent bacterial cystitis and interstitial cystitis are not the same disease. The diagnosis must be clarified prior to treatment.
Our Approach in Our Bodrum Clinic
In evaluation with Dr. Kerem Çağlayan in Bodrum, your complaints, medical history, and current treatments are addressed together. For those seeking information about intravesical ozone in Muğla and Milas, this guide explains the administration process and areas of use.
Related ozone applications
References
- Intravesical ozone in interstitial cystitis: prospective preliminary study. View source
- Bladder mucosa and microcirculation in chronic cystitis under ozone therapy. View source
- AUA Guideline: Interstitial Cystitis/Bladder Pain Syndrome. 2022.
- Madrid Declaration on Ozone Therapy.
